Fenway-Kenmore is an area of Boston, Massachusetts. While it can be considered one neighborhood for administrative purposes, in reality it is composed of numerous neighborhoods with two very different feels, and is rarely referred to as a single entity in casual conversation ("The Fenway," and "Kenmore Square" or simply "Kenmore" are far more commonly spoken). It is the home of Fenway Park, the famous CITGO sign, Kenmore Square, Northeastern University, much of Boston University, Berklee College of Music, The Boston Conservatory, Emmanuel College, Massachusetts College of Art, Simmons College, and the Museum of Fine Arts.

Fenway is a neighborhood bounded on the south by Mission Hill, the Back Bay Fens and Columbus Avenue, on the north by the Mass Pike, and on the west by Mission Hill. Fenway is one of the last middle class neighborhoods left in downtown Boston. The neighborhood almost entirely comprised of five- to six-story walk-up apartment buildings, with small, independently owned shops scattered throughout. Racially, Fenway is predominantly white but also has a large population of Asian & African Americans. The crime-rate in the neighborhood remains relatively low. The neighborhood feels somewhat isolated from the rest of downtown due to the large park and major highway that act as the neighborhood’s boundaries. With its proximity to major parks, Back Bay, Boston University, Northeastern University and the Longwood cultural district, Fenway may be Boston's last untapped real estate gem. Due to aging buildings, a lack of parking and little interest from fellow city dwellers, however, significant real estate development does not appear to be in the near future.